| November 9, 2008 |
Ogden releases Jason Stanford and signs Brandon Duckworth. |
| Philadelphia releases Rodrigo Lopez and Chin-Hui Tsao and signs Josh Towers and Patrick Misch. |
| November 5, 2008 |
Casper releases D'Angelo Jimenez and signs Wes Helms. |
| October 31, 2008 |
Casper signs Randy Messenger and Kameron Loe. |
| Casper releases Clint Sammons and Brandon Watson. |
| October 30, 2008 |
Casper releases Mike Morse and signs Ryan Langerhans. |
| October 24, 2008 |
Folsom releases Roger Clemens and Chris Schroder and signs Henry Blanco and Marlon Anderson. |
| October 21, 2008 |
Ogden releases Ryan Langerhans. |
| Potomac trades Reggie Willits to Ogden for OGD 3rd round pick in 2009 draft. |
| October 15, 2008 |
Philadelphia signs Lew Ford. |
| Ogden trades OGD 6th round pick in 2009 draft to Philadelphia for Nook Logan. |
| Ogden releases Freddie Bynum. |
| October 12, 2008 |
Philadelphia signs Matt Wise. |
| South Elgin releases Dewayne Wise. |
| Philadelphia trades Jeremy Accardo to South Elgin for SEL 4th round pick in 2009 draft. |
| October 9, 2008 |
Westland releases Brian Burres and signs Woody Williams. |
| October 6, 2008 |
Ogden releases Miguel Cairo and signs Brad Wilkerson. |
| Mud City releases Brad Wilkerson. |
| Philadelphia signs Morgan Ensberg. |
| October 2, 2008 |
Philadelphia signs Guillermo Mota. |
| Ogden releases Kenny Rogers and signs Tony Pena Jr. |
| Omaha releases Tony Pena Jr. |
| Omaha trades Stephen Drew and Chris Sampson to Philadelphia for Orlando Cabrera, Doug Brocail, and Brian Bannister. |
| September 28, 2008 |
Mud City trades Michael Bourn and MCM 3rd round pick in 2009 draft to Philadelphia for Brian Giles and Luke Scott. |
| September 26, 2008 |
Delaware releases Marlon Anderson and signs Marcus Giles. |
| Vermont releases Odalis Perez and signs Gary Glover. |
| Philadelphia trades Damion Easley to Eureka for Luke Scott. |
| September 17, 2008 |
Folsom signs John Grabow. |
| September 13, 2008 |
Potomac trades Khalil Greene to Westland for Rafael Furcal. |
| September 12, 2008 |
Big Timber releases Marcus Giles. |
| South Elgin trades Ryan Ludwick, Brandon Inge, and Ramon Vazquez to Philadelphia for Aramis Ramirez, Alan Embree, and Dallas Braden. |
| Big Timber trades Manny Ramirez to Washington for Jeff Francouer, Jason Kendall, and WAS 1st round pick in 2009 draft. |
| September 11, 2008 |
Philadelphia releases Omar Quintanilla. |
| Folsom trades Hong-Chih Kuo, Joey Devine and Mark Hendrickson to Philadelphia for Rich Hill, and Tyler Johnson. |
| August 31, 2008 |
New York trades Jeff Francis to Washington for WAS 3rd round pick in 2009 draft. |
| August 14, 2008 |
Philadelphia trades Aaron Harang to Omaha for Ian Stewart and OMA 1st round pick in 2009 draft. |
| July 22, 2008 |
Ogden releases Zack Duke and signs Matt Belisle. |
| July 13, 2008 |
Folsom trades Lastings Milledge to Omaha for Josh Willingham. |
| July 12, 2008 |
North Shore trades Sean Gallagher, Santiago Casilla, NSL 6th round pick in 2009 draft to Washington for Jake Westbrook and Jeff Clement. |
| Washington trades Bobby Howry to Algonquin for WAS 5th round pick in 2008 draft and ALG 6th round pick in 2008 draft. |
| July 11, 2008 |
North Shore trades John Lannan to Mud City for Aaron Heilman. |
| Big Timber trades BIG 3rd round pick in 2009 draft to Rockland for BIG 4th round pick in 2008 draft. |
| July 10, 2008 |
Folsom trades FOL 3rd round pick in 2008 draft to Tampa Bay for Chad Cordero. |
| July 8, 2008 |
Portland trades Ricky Nolasco and Carlos Quentin to Washington for WAS 1st round pick in 2008 draft. |
| Folsom trades JJ Putz to Tampa Bay for Rickie Weeks and Lastings Milledge. |
| Philadelphia trades Johnny Damon and Mike Mussina to Westland for Rich Hill and WES 6th round pick in 2008 draft. |
| July 3, 2008 |
South Elgin trades SEL 3rd round pick in 2008 draft to North Shore for Tom Gorzelanny. |
| North Shore trades Michael Cuddyer to Washington for POR 6th round pick in 2008 draft. |
| North Shore trades Scott Spiezio to Ogden for Jim Grabow. |
| North Shore trades Kevin Correia to Washington for WAS 3rd round pick in 2008 draft. |
| June 29, 2008 |
Philadelphia trades PHI 5th round pick in 2008 draft to Delaware for Kelly Shoppach. |
| Portland trades Felipe Lopez and Craig Biggio to Ogden for Josh Barfield and Doug Slaten. |
| June 28, 2008 |
Eureka trades Brendan Harris and Chris Ray to Portland for POR 2nd round pick in 2008 draft. |
| Big Timber releases Chan-Ho Park. |
| Tampa Bay trades TBY 3rd round pick in 2008 draft to Philadelphia for Austin Kearns. |
| Big Timber releases Juan Castro. |
| Washington trades Jason Bartlett and Lyle Overbay to Big Timber for BIG 5th round pick in 2008 draft. |
| Philadelphia trades Mark Ellis and Chad Bradford to Tampa Bay for Brian Giles and Xavier Nady. |
| Big Timber trades Craig Biggio to Portland for John McDonald. |
| Westland trades Jason McDonald and Jacque Jones to Portland for POR 3rd and 5th round picks in 2008 draft. |
| Portland trades Todd Jones to Westland for Chad Gaudin. |
| Folsom trades FOL 6th round pick in 2008 draft to Washington for Greg Dobbs. |
| Big Timber trades Troy Glaus to Tampa Bay for TBY 5th round pick in 2008 draft. |
| June 20, 2008 |
Portland releases Jose Mesa. |
| June 18, 2008 |
Washington trades Jarrod Washburn and Matt Morris to Portland for POR 4th and 6th round picks in 2008 draft. |
| June 17, 2008 |
Big Timber releases Neifi Perez. |
| June 16, 2008 |
Big Timber trades BIG 2nd round pick in 2008 draft to Philadelphia for Greg Maddux. |
| June 15, 2008 |
Portland releases Danny Ardoin, Jason Davis, Brad Thompson |
| Ogden releases John Wasdin and Tony Armas. |
| Vermont releases Brad Halsey. |
| Omaha releases Tim Stauffer, Ryan O'Malley and Shane Youman. |
| Westland releases Joe Borchard. |
| June 14, 2008 |
Ogden releases Tommy Murphy. |
| Folsom releases Horacio Ramirez. |
| Omaha releases Brian Bruney and Marty McLeary. |
| June 13, 2008 |
Folsom releases Damon Hollins. |
| Tampa Bay releases Geoff Blum. |
| Westland releases Phil Nevin. |
| Ogden releases Josh Kinney. |
| June 12, 2008 |
Folsom releases Luke Hudson and Roberto Hernandez. |
| June 11, 2008 |
Folsom releases Ben Johnson. |
| Westland releases Ramon Ortiz. |
| Omaha releases Clay Condrey. |